Author: Cassie Martin / Source: Science News
A new microscope is giving researchers an unprecedented view of how mammals are built, cell by cell.
Light sheet microscopes use ultrathin laser beams to illuminate sections of a specimen while cameras record those lit-up sections. Previous iterations of the device have captured detailed portraits of living zebra fish and fruit fly embryos as they develop. Kate McDole, a developmental biologist at Howard Hughes Medical Institute’s Janelia Research Campus in Ashburn, Va., and colleagues used a new-and-improved version to monitor the development of a larger, more complex organism: the mouse.
Algorithms in the microscope tracked six-day-old mouse embryos in real time over roughly two days, keeping the device focused on the cell clusters as they grew. A suite of computer programs…
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