Source: Good News Network
A research team has succeeded in making bioengineered lungs and transplanting them into adult pigs with no medical complications.
The project was carried out by Joan Nichols and Joaquin Cortiella from The University of Texas Medical Branch at Galveston, who, in 2014, were the first research team to successfully bioengineer human lungs in a lab.
Now, in a paper available in Science Translational Medicine, they provide details of how their work has progressed to where no complications have occurred in the pigs as part of standard preclinical testing.
To produce a bioengineered lung, a support scaffold is needed that meets the structural needs of a lung. A support scaffold was created using a lung from an unrelated animal that was treated using a special mixture of sugar and detergent to eliminate all cells and blood in the lung, leaving only the scaffolding proteins or skeleton of the lung behind. This is a lung-shaped scaffold made totally from lung proteins.
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